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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7053ab9d021128c34cac19759b5bf9091f19829630342bee02f5f71c28cee1c' 
  AND token = 'AV/eWOl4Au2Qn1bJJuawGImK2OhhW6Y71EMgr5GA8sQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}