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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '719d656f5e7550809010b63ce7df79b91661737df18d97da2d8d66f0b0408410' 
  AND token = 'JL8VmD2sUI48c4d/Oj2mh7kYCdtLTIj3FsjhT1a0l6k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}