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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc2eac4bcc8603f32d27d4e13f96d9be9f227abf159ff39551f67d40ee0b4c77' 
  AND token = 'K2laKwy6Z3gYwQDHe/bNMVUZQbMCTwEnXayAyiKqp1s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}