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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a51b553c3deabf5f7ac6c44dfb18b29f1c16b59dc8da191363e7c621bac68606' 
  AND token = 'xFW1v8G2NMsMn3YpJO/t4RJtrR3mGWqr7hyxK6UF8k0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}