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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1fc5a43d89bbe78466a56eb59aa89a4d671b76cd3607ae621bf0d32976e759d5' 
  AND token = 'CdZo0QAhpO2wkmVb1Hd8ii/IXLv/AxbwyFIR5nbBpsU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}