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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00d79a1555865c512905466a0e07261cc6a75749ce6e355c13af544324aa7beb' 
  AND token = 'AuRYcyaOhR/EagS+U6xLAVpAO+FNdv1uv200RwmP0sg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}