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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28e59dec45aa2863c59703b8d03e9f067b7576d3fcc4d8f08b43f52065d9aa03' 
  AND token = '9TumCK0CMV/afZ+I8ZJ/Xv2O+vL+cvVVfawZBNb4XOk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00080

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}