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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5d9338526b7ee9afe18a4b0e726fe675d124318552a30587d841001dab0cdd8' 
  AND token = 'Tgx4M3xGUL06byAMhtaWLPt05an8jl1S1UiDyheMhdA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}