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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35abc52cfb3c35324ed08a7a6b78681aeb86a80cefeb127d313ffd49b66fa441' 
  AND token = 'fW6Fib8KppiW+tji1TxXm8t++5DsfFS3ERsvbImSCY0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}