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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ed89b9c28f86777c4d665c14c145478c87d07bd89498f710bf9ac151bcd4a8d' 
  AND token = 'riMOuBeTnC68tbh9b0nSXt+I47yiPrcJaVIkkwL7YMA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}