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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da19ed92d8165d1943b9e3b7400bcc75bed14f09355a02d70e41a5a866983c6c' 
  AND token = 'ZaNkHIEgyPWiZF3sc+O+eGuGapm0vIg5xWQw539bcDI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}