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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '07f443280dfe6b5014f4907ae0d7fa4f4071b40ad621df1bdc80ff3a9a2bbe09' 
  AND token = 'KDeEISZ3DYADmbZbI4LHnTFevnD/kZoDSdlaGRxuEaM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}