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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '85bec7b7b04bcb78a9f43d4c0b8f2e4f3d42e29365212ad98214fd3da8355564' 
  AND token = '4aN1AN5NaQ5zC6KOfNKAWGDY8UR2JnUMUTB8zfraOeo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}