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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74aee1c2ecfce0aa62954be2ef2e666d0af39e5ea111716a50bed0e65d579ea7' 
  AND token = 'e4ZrOcMdV1btPDZ34SB61doR2v8zVEB9aiEPYgMO6dE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}