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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '177857a5b8e8de8f6a996871a30d2d6abc3ebed3d739397d55fca04c1c01ca35' 
  AND token = 'Ptg3yC+xvX0rxhSGso5b4GwJ9ZCBJwuk177mgNoonhM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}