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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c9acc15930aca9e9002c7b796ccda0e8d8ad66c73f729bf93fe3c3f72825a59' 
  AND token = 'a+3Dc0+wKDzTGOcr4x+J6BDOelcio6u5/PQ+jAAi0eU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}