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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '357e9d43a32b1dcfd41a11b2b7a124c1642ebc55702132b2e57fa6bd2652c7fd' 
  AND token = 'RC5s0DqoMCQKwwmvh+SFL2/7c/JXo1IJNkL5Dedgpl0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}