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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e81d81eee85d48d3c6b9003e2325f33dd96bddcb06b21881167116990ef755ae' 
  AND token = 'EzrzgmBZEyCYdZDi1azpH+Mb4AB9PjzQsqN/R73s/Os=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}