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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a16da263daeb1e68351a1291ad0be492c93d685fd9408994177f993f57b2d092' 
  AND token = 'IwGXddtQtf6srzAExfa5NFXz/o65ej5V9cXceiQQMxU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}