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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5168ac3cfff4e0a25cd5d1dddafe98b7f0e6384123583dc8a923cb0ca67e2b58' 
  AND token = 'bRGeED1XkTnAXlAdQWao83lzDxnC+4GLDYBb3f31p1Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}