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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd8f0895b0c279ff1b7216a3c1c36882393aa4fabb7ade9c5748f432dcd0ca85' 
  AND token = 'cfVZXT+LNbWM09UkwtD2CdFi4nvdCrtDotVFt3LZfRk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}