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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1bba299a35205b8895aa2befa974760e1d9c032920d3901a70cd5b1e17d622c' 
  AND token = 'Z901XYwyL2ObSi1EF+/BO2EUvCgypZSiAVBWtk1xiBQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}