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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5721fc40196ec2a2088b65e61d4783e927fe7c2ab26027a4d58cb44d0af7ddc7' 
  AND token = 'IuLfCS7moStb+u4BE39G45KxKOGzXszhmDaonRkVei8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}