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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c335584894c44d65fe22d4d74578ef1d2114197093aebc3da831f9146e0712cc' 
  AND token = '8jPf2aaE86LvSwrXSfTP4h8xsa2df9xASuV3S5S6sEM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}