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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40a465c868844491a8c8a10c6089b826a9b19b0a58bb4d358a7fe91a8304e260' 
  AND token = '5+GB9ijgr6jDNgHCmL8FwyzxkQJvOjMUEs9UNpMXhGc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}