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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7730330e3fb29c235b0398811bc040a81e4a8a8f309766ef5e0a3ea13b13cce6' 
  AND token = 'Oz+424X7Ww6n0WuYRHqS79a2pHpDA9dXFDPgCM+VVg0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}