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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '949505f41b9cae7a4240a33b0320ce65dfdd12a117394031f0aa2da4bcba2906' 
  AND token = 'eZO4IXHeLfPab6WXKv/5+Gl3/w9tubPTO3eMy+TTIqs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}