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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed86b58b67f1a3204aec9a0368fc655102f490029a4b00b628b9f0cc30e9d3c5' 
  AND token = 'ihQy8ysD2wO2/o6G8VBINOLxhhqnSrkNB6JJRXFCG+4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}