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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3de09268312657cb4d1dfd7399e48806f96eb5429ff194c0b9a391250362476' 
  AND token = 'I1FnCkXOmGDa4suCGBtCpUkTMBUqgVfzOBRz3ICI1sg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}