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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd379891a7e55659986fc4d2f3a53893acaed895a71e7bb384b07491788df8d3b' 
  AND token = '6EDEIqjzNFW7WwnlFuQW9BG9CNmF/RvoFKKQ7UaeDN4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}