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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b6d2b8fb05055e69ddbb0ea92662d94b742f8a108b9955f0839ddc9276d3576' 
  AND token = 'ZoosavNGrpqtJt2+PNgO3mP2n4Unyvx21/7gqFiHP/U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}