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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '08525d0e33e66cefd802fd130da67b41ba5aba8737708fa3d03b9161f50e8a2d' 
  AND token = 'mQKhmbnCoi3uMFj2UI9NsyiaSryDzzQwlYiZ/Umh850=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}