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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6ea53ecd9b2dc4b473475cfd88d744bcb61ba1f95d2cca77c2a152a027bade5' 
  AND token = 'DXj+Ql4WNlNo/nuYEd952dpwwflgu/LGrf29dUTi4zM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}