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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c77619ff0651ea1437a3dfb92d2bc06b6c9085182cfd6d4c70058a7403d76ae' 
  AND token = 'n0G8hQ4aOoQEOl16lDKVLfS4FxmaBH4+/UqCro/fbrY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}