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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e2c0f648e7849d7ea7af1036a34c4e673e0d4030802f2443584eb4dd89e1a9d' 
  AND token = 'oJKCnEtuaA2/Ss9Y0e7FpbMV2OgpNTlmZK36nWfrilw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}