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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d15a88039ee63c4fa4f7307530ee3ee0e75638b1e0f26bc7177db9c71abc189' 
  AND token = '+7gtTjlAHRYTDNdNi0rf609BFFbXavgBTwUlPTULhEc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}