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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bb4096af0ffa4d9545dff3563a75fa858e0f157b3cb2c8531ce520fee0c7e143' 
  AND token = 'e6KEbfcWW6n1CN0bbA6u7cEWyqbblZu01hUqT8YOC8I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}