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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2604139864d6d3548f69db5cb4da1896bd78f2af189cc997aeb63d72e3803d9c' 
  AND token = 'nolFlgv+zarppOVp3lv42IoJnJ5tkFFjjuabvAQgxXc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}