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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a48f920e51654d5325920ccdab49058419d3392dd709ec14b9b58eed04ad7728' 
  AND token = 'V9WKHSBiB93wWl2T5afq9Q2aUpkdECujaG3ZcySA/vg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}