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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e902d8d033609ea5186e69e2f2d22379597ad182097fe434a57bce57a3391b1' 
  AND token = 'WsMi3f/9f390u/SQZ51yRzrCMqpkt+6O+wa0CCOS7A4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}