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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0035603be4d00a5a22edb1f070971db1514f1b8060ab75c07e0ed5803a7df86b' 
  AND token = 'MBOKXeY7E/QGPQdwrNM7L9nW+9A8sJPTJ3I+2yNbXBE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}