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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f800ae66f33b2408d798b4b3d7c0fc42bda2545e586a67b409e63a44522c48f3' 
  AND token = 'fFzgCnm6DyDOuyxcz+NdGTtAJVuk2jZ4wXr4CwyolTc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}