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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a6fb71b75bf556302a5b6d00d8ca9f73d193baad81d1eec2a8da74c74fdf434' 
  AND token = 'yn2Aqmydk6SEJVkKo1qxOcbGvMR21hNCYFBOnF+Qi7Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}