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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10a20ba9f0e8c3d7d42d66d15d2aed36ba9b9b9ce4d4d824f9174ed6b50e1273' 
  AND token = 'aLXI73jqG7xY/K2dVMDG1CpUWvfBJK2rO//3MAkjOtU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}