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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e06fd0ea848f2d0ee12363ef54f058f257a86f5be166a784e42c561a30a95db4' 
  AND token = 'Zz3aMjGbbB1QuuCJLm5YzWM3AGzdTptRqg0jcJxHcqY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}