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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f56d6b259fefbc8ad6adc50facf2fa9ed7967e13da1f483021b2d1bad1cde6bb' 
  AND token = '2qCu/qrenYEyJlB1l9JP8qeX8Trb7STAupO+21L/ocE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}