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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd5bb30a22759003e2eb289e3583cccdca9e0d7c41d6c9b26b291078c0b6d278' 
  AND token = '8t0ecAZDImPe8KttfLy3iJSG7f/YkJYkBhlDCWwEhxQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}