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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ddb0d73fd8c998126dc4ef8c0859d9d64b91b97dd218c3db676aa5973f63a094' 
  AND token = 'a1W+jU2M0ZR9lTcc+FPsmRjCSzKdY8diVIDVN2DvXP0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}