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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4db2e832734d1a38795fe32ff8cd2ec645f1c18c3df605526c6d566b4e096c04' 
  AND token = 'dKST74Oc3uhTHt6eDBNPXQsVvhLkV+q7WKNJBeuE4jQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}