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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b2bb416380967635706b45e36fab75e8779b02c3ae98f7072bac22a9e74b650' 
  AND token = 'hPnYfxg+YIj2sZMoVoQi8JSZsRQ7UXFV2Lcp9iPPe14=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}